Fentanyl Citrate Injection is a potent, short-acting Schedule II (CII) controlled synthetic opioid agonist primarily utilized for surgical analgesia, anesthesia induction, and immediate postoperative pain management. Because of its extreme potency—50 to 100 times more potent than morphine—it must only be administered by medical professionals specifically trained in intravenous anesthetics and airway management. Clinical Indications
Fentanyl citrate injection is indicated in clinical hospital settings for:

• Anesthesia Supplement: Used as a narcotic analgesic adjunct in general or regional anesthesia.
• Short-Duration Analgesia: Administered during preoperative premedication, induction, maintenance, and the immediate postoperative recovery period.
• Primary Anesthetic Agent: Given with 100% oxygen in high-risk procedures, such as cardiothoracic surgery or complicated neurosurgery 
• Concentration:< /strong> Typically 50 mcg of fentanyl base per mL (equivalent to 78.5 mcg fentanyl citrate per mL).
• Available Forms: Single-dose glass ampules, fliptop vials, and prefilled syringes ranging from 1 mL to 50 mL.
• Adult Dosing: Initial doses generally range from 50 mcg to 100 mcg intravenously (IV) or intramuscularly (IM).
• Pediatric Dosing (Ages 2–12): Initiated at a reduced weight-based dose of 2 mcg/kg to 3 mcg/kg.

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